Severe pneumococcal pneumonia with human rhinovirus/enterovirus coinfection leading to sepsis in a welder: a case report - Summary - MDSpire

Severe pneumococcal pneumonia with human rhinovirus/enterovirus coinfection leading to sepsis in a welder: a case report

  • By

  • Pavlina Peneva

  • Greta Kossian

  • Leon Nedelcev

  • Richard Coveney

  • Pavel Yordanov

  • Valentina Dimitrova

  • Petar Georgiev

  • Nikoleta Mircheva

  • Figen Mustafa

  • Anton Antonov

  • Miglena Tzenova

  • Antoanina Botseva

  • Nadezhda Ilieva

  • Velislava Tasheva

  • Yulia Doga

  • Diana Petkova

  • Tanya Dobreva

  • July 13, 2026

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Objective:

To present a case of severe pneumonia due to Streptococcus pneumoniae complicated by HRV/HEV coinfection.

Approach:
  • Patient Presentation: A 64-year-old male welder with a history of smoking and no prior vaccinations presented with severe pneumonia and hypoxemia.
  • Diagnostic Assessment: Microbiological investigations confirmed invasive pneumococcal disease and HRV/HEV infection, leading to a dysregulated inflammatory response and sepsis.
Key Findings:
  • The patient exhibited severe right lobar pneumonia with Streptococcus pneumoniae bacteremia and HRV/HEV coinfection.
  • Clinical course included prolonged hospitalization and fluctuating symptoms despite early antibiotic therapy.
  • The interplay of viral and bacterial infections contributed to systemic inflammation, coagulopathy, and multiorgan dysfunction.
Interpretation:

Limitations:
  • Limited data on HRV/HEV infections in low- and middle-income countries.
  • Case report format limits generalizability of findings.
Conclusion:

Original Source(s)

Severe pneumococcal pneumonia with human rhinovirus/enterovirus coinfection leading to sepsis in a welder: a case report

  • by Pavlina Peneva, Greta Kossian, Leon Nedelcev, Richard Coveney, Pavel Yordanov, Valentina Dimitrova, Petar Georgiev, Nikoleta Mircheva, Figen Mustafa, Anton Antonov, Miglena Tzenova, Antoanina Botseva, Nadezhda Ilieva, Velislava Tasheva, Yulia Doga, Diana Petkova, Tanya Dobreva

  • July 13, 2026

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