Objective:

To describe the clinical characteristics and outcomes of enterococcal bacteraemia in a high-risk cohort and analyze differences between E. faecalis and E. faecium bacteraemia.

Approach:

Key Findings:

• Enterococcal bacteraemia is associated with high mortality rates, particularly in immunocompromised patients.
• The DENOVA score demonstrated high sensitivity (100%) and specificity (up to 85%) for identifying patients needing echocardiography for endocarditis.
• Differences in clinical characteristics and outcomes were noted between E. faecalis and E. faecium bacteraemia.

Interpretation:

Limitations:

• The study was conducted in a single medical center, which may limit the generalizability of the findings.
• The DENOVA score was only validated for monomicrobial E. faecalis bacteraemia, raising questions about its applicability to other types.

Conclusion:

Attribution Notice

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