Objective:

To examine hyperkalemia recurrence and identify independent baseline risk factors for hyperkalemia recurrence in patients with heart failure (HF).

Approach:

Key Findings:

• 49.5% of the full cohort experienced recurrent hyperkalemia within 12 months.
• 37.3% recurrence rate in the No-CKD subgroup.
• Mean number of recurrences was 2.5 for the full cohort and 2.0 for the No-CKD subgroup.
• Mean potassium level at each recurrence was approximately 5.5 mmol/L.
• Significant risk factors for recurrence included history of hyperkalemia (OR 2.3), hypertension, advanced CKD, immunosuppressant therapy, and malignancy.

Interpretation:

Limitations:

• The study is observational and may not establish causality.
• Data is derived from EHR, which may have limitations in accuracy and completeness.

Conclusion:

Attribution Notice

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