To report a case of interstitial lung disease in a solar panel processing worker with indium-tin-oxide exposure, pathologically confirmed as pulmonary alveolar proteinosis (PAP) that progressed to pulmonary fibrosis after diagnosis.
Key Findings:
The patient had significantly elevated indium levels in bronchoalveolar lavage fluid and plasma, indicating potential toxicity.
Despite undergoing whole-lung lavage, the patient developed progressive pulmonary fibrosis.
Nintedanib treatment showed no significant effect on lung function decline.
Interpretation:
The case suggests a potential link between ITO exposure and the development of PAP, highlighting the urgent need for protective measures, such as improved ventilation and personal protective equipment, in occupational settings.
Limitations:
The study is based on a single case, limiting generalizability.
Long-term outcomes and the effectiveness of treatments for ITO-related lung diseases remain unclear, with no follow-up data available.
Conclusion:
Diagnosis of PAP should be considered in patients with a history of indium exposure, and protective measures are essential to mitigate risks of lung disease.
