Case Report: Recurrent cerebral embolism secondary to direct cardiac invasion by lung adenocarcinoma - Summary - MDSpire

Case Report: Recurrent cerebral embolism secondary to direct cardiac invasion by lung adenocarcinoma

  • By

  • Xiangxiong Wu

  • Shenwen He

  • Yayao Huo

  • Yuying Wu

  • Xiaoying Li

  • Ying Yang

  • Dawei Dong

  • June 24, 2026

  • 0 min

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Objective:

To report a rare case of recurrent cerebral embolism caused by direct cardiac invasion by lung adenocarcinoma.

Approach:
  • Case Description: A 41-year-old woman presented with acute right-sided hemiparesis and aphasia, diagnosed with left middle cerebral artery occlusion and treated with mechanical thrombectomy. A second embolic stroke occurred four days later, leading to further investigation reve…
Key Findings:
  • The patient experienced two embolic strokes within a week, both resolved via thrombectomy.
  • Imaging revealed a right lung adenocarcinoma infiltrating the pericardium, pulmonary vein, and left atrium.
  • No further embolic events occurred during follow-up after chemotherapy and anticoagulation.
Interpretation:

This case highlights the importance of considering tumor-related stroke in younger patients without traditional risk factors.

Limitations:
  • The case is based on a single patient, limiting generalizability.
  • Further investigations were declined by the patient post-discharge.
Conclusion:

This case illustrates a rare cause of recurrent cerebral embolism due to direct cardiac invasion by lung adenocarcinoma.

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