To retrospectively compare the effectiveness and safety of neuroendoscopic surgery (NS) and stereotactic aspiration (SA) in treating intraparenchymal hemorrhage (IPH) across various anatomical locations.
Key Findings:
NS had a significantly higher median hematoma reduction rate (92.90% vs. 22.20%, p < 0.001), indicating superior efficacy.
Greater acute neurological improvement was observed in NS (median ΔGCS 4.0 vs. 0.5 points, p < 0.001), suggesting better early recovery.
Functional independence at discharge was achieved by 27.8% in the NS group vs. 15.7% in the SA group (p = 0.040), highlighting the potential for improved patient outcomes.
NS was associated with lower rates of symptomatic rebleeding (7.2% vs. 24.5%, p < 0.001) and 30-day mortality (9.3% vs. 22.5%, p = 0.012), underscoring its safety profile.
Interpretation:
NS is associated with higher evacuation efficiency and improved early neurological recovery compared to SA across various IPH locations, suggesting significant advantages for clinical practice in terms of direct visualization and active hemostasis.
Limitations:
Retrospective design may introduce selection bias, potentially affecting the generalizability of the findings.
Findings require prospective validation to confirm long-term functional outcomes and to address the limitations of retrospective analyses.
Conclusion:
NS may offer significant benefits over SA in managing IPH, warranting further prospective studies to confirm these results.
