Integrated neuropsychological assessment in patients undergoing neurosurgical and endovascular treatment of unruptured cerebral aneurysms: results of a prospective observational study - Summary - MDSpire

Integrated neuropsychological assessment in patients undergoing neurosurgical and endovascular treatment of unruptured cerebral aneurysms: results of a prospective observational study

  • By

  • Marco Galeazzi

  • Rina Di Bonaventura

  • Fulvio Vincenzo Grilli

  • Martina Silvestri

  • Alessandro Olivi

  • Enrico Marchese

  • Alessio Albanese

  • February 24, 2026

  • 0 min

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Objective:

To evaluate cognitive outcomes following surgical and endovascular treatment for unruptured cerebral aneurysms, emphasizing their significance in patient quality of life.

Key Findings:
  • No significant cognitive dysfunctions were observed post-treatment in both surgical and endovascular groups, indicating effective preservation of cognitive function.
  • Endovascular coiling resulted in fewer cognitive deficits compared to surgical clipping, suggesting a potential advantage in treatment choice.
  • Treatment improved symptoms of anxiety and depression in patients, highlighting the psychological benefits of intervention.
Interpretation:

The study suggests that both surgical and endovascular treatments for unruptured cerebral aneurysms do not significantly impair cognitive function and may enhance emotional well-being, with implications for clinical practice.

Limitations:
  • Small sample size and potential selection bias due to non-participation, which may affect the generalizability of the findings.
  • Heterogeneous patient population and aneurysm characteristics, which could influence cognitive outcomes.
  • Lack of long-term follow-up assessments, necessitating further research to confirm findings.
Conclusion:

This study provides valuable insights into cognitive outcomes following treatment of unruptured cerebral aneurysms, indicating that modern interventions may preserve cognitive function and improve psychological health, while underscoring the need for further research.

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