Three-Dimensional Transthoracic Echocardiography as a Tool for Patient Selection for Percutaneous Atrial Septal Defect Closure - Summary - MDSpire
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Utilizing Three-Dimensional Transthoracic Echocardiography for Selecting Candidates for Percutaneous Closure of Atrial Septal Defects

  • By

  • Talya Finke

  • Uriel Katz

  • Tal Grupel

  • Yarden Sarouf Gat

  • Gur Mainzer

  • Sharon Borik Chiger

  • September 12, 2026

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Objective:

To evaluate the impact of three-dimensional transthoracic echocardiography on patient selection for percutaneous atrial septal defect repair.

Approach:
  • Study Design: A single-center retrospective analysis was conducted at Safra Children’s Hospital, Sheba Medical Center, Israel, from June 2021 through May 2024, focusing on the impact of three-dimensional transthoracic echocardiography on patient selection.
Key Findings:
  • 36 patients aged 1–44 years were included in the study, with a median age of 6 years.
  • 42% of patients were referred for surgical closure due to unsuitable anatomy for percutaneous intervention.
  • 36% of patients underwent referral for three-dimensional transthoracic echocardiography after inconclusive initial imaging.
Interpretation:

Three-dimensional transthoracic echocardiography may assist in the selection of candidates for percutaneous closure without sedation, potentially improving patient outcomes.

Limitations:
  • The study was conducted at a single center, which may limit the generalizability of the findings.
  • The retrospective nature of the analysis may introduce selection bias.
Conclusion:

Three-dimensional transthoracic echocardiography provides valuable insights for selecting candidates for percutaneous atrial septal defect repair.

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