To report a case of Sertoli cell tumor in a patient with genetically confirmed familial adenomatous polyposis (FAP) and colonic adenocarcinoma.
Approach:
Treatment and Follow-Up: After colectomy, the patient received adjuvant chemotherapy with capecitabine and oxaliplatin, which was well tolerated, although a dose reduction was necessary due to neuropathy.
Key Findings:
The patient had a Sertoli cell tumor associated with a pathogenic APC mutation linked to familial adenomatous polyposis.
Histopathological examination showed the tumor lacked high-risk features.
Beta-catenin expression was noted, indicating potential Wnt pathway activation.
Limitations:
The study is based on a single case report, limiting generalizability.
