Objective:

To evaluate the effectiveness of heat-inactivated Lactiplantibacillus pentosus ONRICb0240 gummies in reducing gingival inflammation in adults.

Approach:

Key Findings:

• Bleeding on probing decreased from 17.6% to 12.3% in the treatment group, compared to little change in the placebo group.
• Gingival index scores improved, while pocket depth, attachment levels, plaque scores, and saliva production remained largely unchanged.
• Participants with a BMI of at least 22 kg/m² and lower baseline bleeding showed the strongest responses.

Interpretation:

The gummies were effective in reducing signs of gingival inflammation without safety concerns.

Limitations:

• The study did not assess long-term effects beyond the 6-week period.
• The sample size was limited to 116 adults.

Conclusion:

Heat-inactivated Lactiplantibacillus pentosus ONRICb0240 gummies may be a beneficial adjunct to oral hygiene for reducing gingival inflammation.

Sources:

• Journal of Periodontology
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