The Take 5 Campaign: Effects of an Intervention to Promote Five-Day Durations of Antibiotic Therapy for Common Infections in Urgent Care - Summary - MDSpire
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The Take 5 Campaign: Effects of an Intervention to Promote Five-Day Durations of Antibiotic Therapy for Common Infections in Urgent Care
To evaluate the effects of the Take 5 initiative on prescribed durations of antibiotic therapy and clinical outcomes, including rates of new prescriptions and hospitalizations, in urgent care settings.
Key Findings:
The intervention led to an immediate 10.7% increase in prescriptions for ≤5 days (P < .001), indicating a significant shift in prescribing behavior.
The aggregate proportion of prescriptions for ≤5 days increased from 57.5% to 82.9% after the intervention (P < .001), demonstrating the campaign's effectiveness.
Rates of new antibiotic prescriptions and hospitalizations within 14 days were similar before and after the intervention, suggesting no adverse effects from the reduced duration.
Interpretation:
The Take 5 campaign effectively increased the adoption of 5-day antibiotic durations, suggesting that shortening therapy durations can reduce unnecessary antibiotic exposure in urgent care settings.
Limitations:
The study was limited to two urgent care centers, which may affect generalizability to other settings.
Data on long-term clinical outcomes beyond 14 days post-prescription were not assessed, which could overlook potential complications.
Conclusion:
The Take 5 initiative successfully promoted shorter antibiotic treatment durations, aligning with antibiotic stewardship goals to minimize unnecessary antibiotic use and suggesting a model for similar interventions in other settings.
by Timothy C Jenkins, Axel A Vazquez Deida, Lindsey E Fish, Michael J Breyer, Amy Quinones, Melody Zwakenberg, Cory K Hussain, Allison L Sabel, Katherine C Shihadeh
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