Greater amounts of visceral adipose and lean body mass increase heart failure risk in older women - Summary - MDSpire

Greater amounts of visceral adipose and lean body mass increase heart failure risk in older women

  • By

  • Michael J. LaMonte

  • Charles B. Eaton

  • Bernhard Haring

  • Jennifer W. Bea

  • Connor R. Miller

  • JoAnn E. Manson

  • Deepika Laddu

  • Marcia L. Stefanick

  • Andrew Odegaard

  • May 26, 2026

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Objective:

To determine associations of body composition with incident heart failure (HF), HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF) in older women.

Approach:
    Key Findings:
    • Higher levels of visceral fat were associated with increased risk of heart failure among older women.
    • Lean mass was found to have a protective effect against heart failure.
    Interpretation:

    Limitations:
    • The study may not generalize to all older women due to its specific cohort.
    • Potential biases in self-reported data and the timing of HF adjudication may affect results.
    Conclusion:

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