HFpEF risk assessment using H2FPEF score in community-dwelling young Hispanic adults - Summary - MDSpire

HFpEF risk assessment using H2FPEF score in community-dwelling young Hispanic adults

  • By

  • Andrew Kim

  • Fadi I. Musfee

  • Soumya Patnaik

  • Miryoung Lee

  • Emma Molina

  • David D. McPherson

  • Joseph B. McCormick

  • Susan P. Fisher-Hoch

  • Susan T. Laing

  • May 29, 2026

  • 0 min

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Objective:

To apply the H2FPEF score to a community-dwelling Hispanic cohort and define demographic and clinical covariate associations, particularly in asymptomatic young Hispanic adults.

Key Findings:
  • 43% of the sample (n = 555) had intermediate-high H2FPEF scores.
  • 33% of participants <60 years had intermediate-high H2FPEF scores.
  • Significant associations with increased H2FPEF scores in young Hispanics included age, metabolic syndrome, higher hemoglobin A1c, and sedentary lifestyle.
Interpretation:

A substantial proportion of young Hispanics in the cohort exhibited intermediate-high H2FPEF scores, indicating a potential risk for HFpEF, which underscores the need for targeted public health interventions.

Limitations:
  • The study is limited to a specific geographic area and demographic, which may affect generalizability.
  • The cross-sectional nature of the study limits causal inferences.
  • Potential biases in self-reported data may affect the accuracy of the findings.
Conclusion:

The H2FPEF score may be a useful tool for identifying HFpEF risk in young Hispanic adults, highlighting the need for targeted cardiometabolic risk management.

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