Association of advanced therapies for intermediate- to high-risk pulmonary embolism with improved right ventricular function on outpatient follow-up among survivors - Summary - MDSpire

Association of advanced therapies for intermediate- to high-risk pulmonary embolism with improved right ventricular function on outpatient follow-up among survivors

  • By

  • Hammad Sheikh

  • Avinash Singh

  • Connor Smith

  • Howard Freeman

  • Abdul Rehman

  • Jeeyune Bahk

  • Sakul

  • Keshav Dixit

  • Alvin Yang

  • Maria Riasat

  • Robert Lookstein

  • Edgar Argulian

  • David J. Steiger

  • June 10, 2026

  • 0 min

Share

Objective:

To investigate the association of receipt of advanced therapies with echocardiographic parameters of RV function at outpatient follow-up among survivors of acute PE.

Approach:
    Key Findings:
    • 122 patients included with median age 64.4 years and median PESI score 86.
    • Advanced therapies (CDE, CDT, SPE) were performed in 17.2%, 9.0%, and 9.0% of cases respectively, with a total of 21, 11, and 11 patients receiving each therapy.
    • Receipt of advanced therapy was associated with increased RVOT VTI (4.6 cm; p = 0.009) and RV Ś (2.0 cm/s; p = 0.006).
    • Higher odds of TR grade improvement were observed (marginal OR: 3.0; p = 0.002).
    Interpretation:

    Limitations:
    • Retrospective, non-randomized design.
    • Modest sample size.
    • Use of surrogate endpoints.
    Conclusion:

Original Source(s)

Association of advanced therapies for intermediate- to high-risk pulmonary embolism with improved right ventricular function on outpatient follow-up among survivors

  • by Hammad Sheikh, Avinash Singh, Connor Smith, Howard Freeman, Abdul Rehman, Jeeyune Bahk, Sakul, Keshav Dixit, Alvin Yang, Maria Riasat, Robert Lookstein, Edgar Argulian, David J. Steiger

  • June 10, 2026

Related Content

Psychiatric events induced by roflumilast: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System database

Evolution of advanced revascularization strategies for high-risk pulmonary embolism: a physiology-guided single-center experience

Specialty Areas in Respiratory Care that Offer a Slower Pace