Assessment of Corneal Optical Densitometry and Anterior Segment Characteristics in a Healthy Upper Egyptian Cohort: A Prospective Observational Cross-Sectional Analysis - Summary - MDSpire
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Assessment of Corneal Optical Densitometry and Anterior Segment Characteristics in a Healthy Upper Egyptian Cohort: A Prospective Observational Cross-Sectional Analysis

  • By

  • Mohamed A. Hamid

  • Mohamed Esmail Khalil Esmail

  • Hosny A. Zein

  • December 1, 2025

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Objective:

To evaluate the associations between corneal optical densitometry (COD) and various biometric parameters in healthy Upper Egyptian subjects.

Approach:
    Key Findings:
    • Study included 379 eyes from 379 subjects, with a mean age of 33 years.
    • Mean spherical equivalent was -2.1 D, with 55.9% of participants being myopic.
    • Significant differences in COD were observed across different age groups.
    Interpretation:

    The study provides insights into the relationship between COD and biometric parameters in a healthy Upper Egyptian population, highlighting the importance of regional studies in understanding corneal health.

    Limitations:
    • Cross-sectional design limits causal inferences.
    • Results may not be generalizable to other populations due to ethnic and environmental differences.
    Conclusion:

    The findings underscore the relevance of COD in assessing corneal health and its associations with age and refractive error in a specific cohort.

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