The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010–2019 - Summary - MDSpire

The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010–2019

  • By

  • Jakhongir F. Alidjanov

  • Tommaso Cai

  • Riccardo Bartoletti

  • Gernot Bonkat

  • Franck Bruyère

  • Béla Köves

  • Ekaterina Kulchavenya

  • José Medina-Polo

  • Kurt Naber

  • Tamara Perepanova

  • Adrian Pilatz

  • Zafer Tandogdu

  • Truls E. Bjerklund Johansen

  • Florian M. Wagenlehner

  • February 22, 2021

  • 0 min

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Objective:

To identify temporal trends in infective complications after prostate biopsy (P-Bx) from 2010 to 2019 and analyze aspects of antimicrobial stewardship, emphasizing their clinical significance.

Key Findings:
  • Infective complications rates after P-Bx ranged from 1.9% to 27.7%, with a notable increase over the years, indicating a growing concern for patient safety.
  • 5.2% of men experienced symptomatic urinary tract infections (UTI) post-P-Bx, highlighting the need for effective monitoring.
  • Antimicrobial resistance (AMR) among uropathogens has led to increased failure of antibiotic prophylaxis, necessitating urgent action in antimicrobial stewardship.
Interpretation:

The study highlights the rising rates of infective complications post-P-Bx and the challenges posed by AMR, emphasizing the need for improved antimicrobial stewardship practices tailored to local resistance patterns.

Limitations:
  • Data collection was limited to specific years, with a gap in 2015, which may affect the continuity of trends.
  • The number of participating centers decreased over the study period, potentially affecting data representativeness and generalizability.
Conclusion:

The findings underscore the importance of monitoring infective complications and implementing effective antimicrobial stewardship in urology to enhance patient outcomes.

Original Source(s)

The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010–2019

  • by Jakhongir F. Alidjanov, Tommaso Cai, Riccardo Bartoletti, Gernot Bonkat, Franck Bruyère, Béla Köves, Ekaterina Kulchavenya, José Medina-Polo, Kurt Naber, Tamara Perepanova, Adrian Pilatz, Zafer Tandogdu, Truls E. Bjerklund Johansen, Florian M. Wagenlehner

  • February 22, 2021

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