Evaluation of Visual and Refractive Outcomes Between Two Advanced Monofocal Intraocular Lenses - Summary - MDSpire
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Evaluation of Visual and Refractive Outcomes Between Two Advanced Monofocal Intraocular Lenses

  • By

  • Hyeck-Soo Son

  • Sang Yoon Kim

  • Kyungmin Koh

  • Gerd U. Auffarth

  • Grzegorz Łabuz

  • January 16, 2026

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Objective:

To analyze and compare the visual and refractive outcomes of the Isopure 1.2.3 (ISP) IOL and the Eyhance® (EH) IOL in Korean cataract patients, highlighting the significance of this comparison in clinical practice.

Key Findings:
  • The ISP IOL demonstrated improved intermediate visual performance compared to the EH IOL, with a statistically significant difference.
  • Both IOLs provided satisfactory visual outcomes, but the ISP IOL showed a slight advantage in depth of focus, with mean values reported.
  • Refractive accuracy was assessed using prediction error and mean absolute error metrics, with specific values provided.
Interpretation:

The study suggests that the ISP IOL may offer better intermediate vision and depth of focus compared to the EH IOL, which could enhance patient satisfaction post-cataract surgery, indicating a potential shift in clinical practice.

Limitations:
  • Retrospective design may introduce selection bias, and the short follow-up duration may not capture long-term outcomes, which could limit the generalizability of the findings.
Conclusion:

The ISP IOL may provide superior visual outcomes in terms of intermediate vision compared to the EH IOL, warranting further studies for validation to confirm these findings.

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