Comparison of Nurse-led Interventions and Standard Care on Cardiovascular Risk Factors in Coronary Artery Disease Patients: A Meta-Analysis of Randomized and Observational Studies - Summary - MDSpire
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Comparison of Nurse-led Interventions and Standard Care on Cardiovascular Risk Factors in Coronary Artery Disease Patients: A Meta-Analysis of Randomized and Observational Studies

  • By

  • Jing Yang

  • Yun Gao

  • Chao Ping Yu

  • Bo Zhang

  • Li Juan Zou

  • Zhu Yan

  • December 11, 2025

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Objective:

To evaluate the impact of nurse-led interventions compared to standard care on cardiovascular risk factors in patients with coronary artery disease (CAD), highlighting the significance of these factors in patient outcomes.

Key Findings:
  • Nurse-led interventions significantly improved cardiovascular risk factors compared to standard care, with notable statistical significance.
  • Improvements were noted in cholesterol levels, blood pressure, BMI, and smoking cessation rates, with effect sizes provided.
  • The meta-analysis included diverse populations, enhancing the generalizability of the findings.
Interpretation:

Nurse-led interventions are effective in managing cardiovascular risk factors in CAD patients, suggesting a valuable role for nurses in cardiac rehabilitation and the need for integration into standard care practices.

Limitations:
  • Potential bias in study selection and outcome measurement, which may affect the reliability of the findings.
  • Variability in intervention protocols and follow-up durations across studies, impacting comparability.
  • Limited inclusion of non-English studies may affect the comprehensiveness of the findings and their applicability to non-English speaking populations.
Conclusion:

Nurse-led interventions are beneficial in reducing cardiovascular risk factors in CAD patients, supporting their integration into standard care practices and suggesting areas for future research.

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