To compare the surgical outcomes of minimally invasive hepatectomy (MIH) with open hepatectomy (OH) in obese patients with liver tumors.
Approach:
Key Findings:
MIH was associated with a shorter operative time (WMD = -54.50, P = 0.01).
MIH resulted in reduced blood loss (WMD = -416.80, P < 0.00001) and a lower blood transfusion rate (OR = 0.31, P < 0.00001).
MIH had lower rates of overall complications (OR = 0.60, P < 0.0001) and major complications (OR = 0.61, P = 0.01).
MIH showed lower rates of biliary leakage (OR = 0.48, P = 0.02) and liver failure (OR = 0.26, P = 0.04).
Patients undergoing MIH had a shorter postoperative hospital stay (WMD = -7.21, P < 0.00001) and smaller tumor size (WMD = -1.06, P = 0.001).
No significant difference in mortality was observed between MIH and OH groups (OR = 0.68, P = 0.07).
Interpretation:
MIH appears to be a safe and effective treatment option for obese patients with liver tumors, offering several advantages over OH, particularly in terms of postoperative recovery and complication rates.
Limitations:
The analysis included only studies that met specific inclusion criteria, which may limit generalizability.
Variability in surgical techniques and definitions of complications across studies may affect outcomes.
Conclusion:
MIH is associated with improved surgical outcomes compared to OH in obese patients with liver tumors, although mortality rates are similar between the two approaches.