The Flu Vaccine Face-Off Ends in a Draw - Summary - MDSpire
From the Journals
Clinical Guidelines

The Flu Vaccine Face-Off Ends in a Draw

  • By

  • Kerri Miller

  • May 8, 2026

  • 5 min

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A large pragmatic study evaluated the effectiveness of adjuvanted versus high-dose influenza vaccines in adults aged 65 years and older during the 2023-2024 season. The research involved 429,595 Kaiser Permanente Northern California patients, revealing similar effectiveness rates for both vaccine formulations against laboratory-confirmed influenza. This study supports ongoing recommendations for either formulation as part of routine care, pending further analyses. The findings emphasize the importance of continued vaccination efforts, especially in older populations vulnerable to influenza.

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