Development of Arthritis in a Large Real-World Cohort of Patients With Pediatric Onset Psoriasis - Summary - MDSpire

Development of Arthritis in a Large Real-World Cohort of Patients With Pediatric Onset Psoriasis

  • By

  • Malak Al-Gawahiri

  • Elke M. G. J. de Jong

  • Ellen J. H. Schatorjé

  • Esther P. A. H. Hoppenreijs

  • Juul M. P. A. van den Reek

  • Marieke M.B. Seyger

  • April 25, 2026

  • 0 min

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Objective:

To describe a real-world cohort of pediatric patients with psoriasis who subsequently developed psoriatic arthritis (JPsA/PsA), focusing on their clinical features and timing of onset.

Approach:
    Key Findings:
    • Only one claims-based study reported that 2% of children with psoriasis developed JPsA during a mean follow-up of 5 years.
    • Older age at first psoriasis diagnosis and presence of uveitis were identified as risk factors for developing JPsA.
    Interpretation:

    The study highlights the need for further understanding of the clinical features and risk factors for developing psoriatic arthritis in pediatric patients with psoriasis.

    Limitations:
    • The cohort primarily consists of patients from a single center, which may limit generalizability.
    • Statistical comparisons were not made due to low numbers of patients with JPsA/PsA.
    Conclusion:

    The findings emphasize the importance of monitoring pediatric patients with psoriasis for potential development of psoriatic arthritis.

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