Seasonal Incidence of Medically Attended Respiratory Syncytial Virus Infection From 2015 to 2019 in a Cohort of Adults With High-risk Conditions - Summary - MDSpire
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Seasonal Incidence of Medically Attended Respiratory Syncytial Virus Infection From 2015 to 2019 in a Cohort of Adults With High-risk Conditions
To assess the seasonal incidence of RSV in adults with high-risk conditions, including chronic respiratory diseases, cardiovascular diseases, and immunocompromised states, in a Wisconsin community.
Key Findings:
Identified 303 RSV infections among 3601 respiratory samples tested.
Estimated incidence of RSV-related MAARI was 94.1 (79.5–111.5) per 10,000 high-risk adults across all seasons.
Incidence varied by age group: 69.3 (52.4–91.7) for 18-49 years, 131.6 (92.3–187.6) for 50-59 years, 109.9 (80.2–150.6) for 60-74 years, and 150.5 (100.8–224.6) for ≥75 years.
Interpretation:
Findings suggest a substantial incidence of RSV-related MAARI in adults with high-risk conditions, highlighting the need for increased awareness, potential interventions, and public health strategies.
Limitations:
Potential underdiagnosis of RSV in adults due to nonspecific symptoms.
RSV testing not routinely conducted in outpatient settings.
Study limited to a specific geographic area, which may affect generalizability to other regions.
Conclusion:
The study underscores the significant burden of RSV in high-risk adults, necessitating further research and consideration for vaccine strategies.
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