Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis - Summary - MDSpire
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Development and evaluation of a preliminary risk assessment model for psychological distress among patients with brain tumors: a cross-sectional analysis

  • By

  • Ying Li

  • Yuyu Duan

  • Yangmei Su

  • Zhiman Zheng

  • Dongqi Zou

  • Zhihuan Zhou

  • January 22, 2026

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Objective:

To construct and validate a predictive model for psychological distress (PD) in brain tumor patients, focusing on the roles of financial toxicity, self-efficacy, and medical coping strategies, specifically addressing the model's parameters and expected outcomes.

Approach:
    Key Findings:
    • 44.5% to 76.0% of brain tumor patients experience clinically significant psychological distress, indicating a critical need for intervention.
    • Financial toxicity is strongly associated with psychological distress among patients and caregivers, highlighting the need for financial support.
    • Higher self-efficacy correlates with reduced psychological distress and improved quality of life, suggesting areas for therapeutic focus.
    • Adaptive coping strategies mitigate psychological distress, while avoidance strategies can exacerbate it, emphasizing the importance of coping education.
    Interpretation:

    The model highlights the importance of addressing financial toxicity and enhancing self-efficacy and coping strategies to reduce psychological distress in brain tumor patients, with implications for clinical practice and patient support.

    Limitations:
    • Single-center study may limit generalizability, potentially affecting the applicability of findings to broader populations.
    • Convenience sampling could introduce selection bias, which may influence the study's conclusions.
    Conclusion:

    Early identification and intervention for psychological distress in brain tumor patients are crucial for improving their quality of life and treatment outcomes.

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