Objective:

To assess the predictive value of Atherogenic Index of Plasma (AIP) control status for the risk of cardiometabolic multimorbidity (CMM) in Chinese middle-aged and elderly populations, highlighting its potential role in early intervention.

Key Findings:

• Dynamic changes in AIP were associated with the risk of developing CMM, suggesting a need for regular monitoring.
• Cumulative AIP exposure was a better predictor of CMM than single measurements, indicating the importance of longitudinal data.
• Longitudinal AIP trajectories provided insights into the progression of CMM, emphasizing the role of AIP in patient management.

Interpretation:

The study highlights the importance of monitoring AIP over time as a potential indicator for early intervention in CMM among older adults.

Limitations:

• The study is limited to a specific population in China, which may affect generalizability; further research is needed in diverse populations.
• Potential confounding factors may not have been fully accounted for, which could influence the results.

Conclusion:

Longitudinal monitoring of AIP may serve as a valuable tool for predicting and managing cardiometabolic multimorbidity in older adults.