Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation - Summary - MDSpire

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation

  • By

  • Gabriel D. Rodrigues

  • Earric Lee

  • Benoit Dugué

  • Christian Hanshans

  • Maria Chiara Maccarone

  • Konstantinos Triantafyllias

  • Arnulf Hartl

  • Eugenijus Kaniusas

  • Sabrina Mörkl

  • Thomas E. Schmid

  • Goda-Camille Mickeviciute

  • Hannes Untner

  • Werner Klingler

  • Martin Offenbächer

  • June 24, 2026

  • 0 min

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Objective:

To synthesize current clinical evidence on radon balneotherapy in managing rheumatologic conditions and explore its physiological mechanisms.

Approach:
  • Literature Review: A narrative synthesis was conducted to integrate literature from clinical rheumatology, low-dose radiobiology, autonomic physiology, and balneology.
  • Search Strategy: A comprehensive literature search was performed using PubMed, Scopus, and Web of Science, focusing on keywords related to radon balneotherapy and its effects on rheumatologic diseases.
  • Study Selection: Eligible articles included peer-reviewed research on therapeutic effects of radon exposure, autonomic nervous system modulation, and anti-inflammatory mechanisms.
Key Findings:
  • Radon balneotherapy combines low-dose radon exposure with immersion in mineral-rich waters, potentially producing systemic health effects.
  • The therapy may influence redox modulation, immune regulation, and autonomic nervous system balance.
  • There is a historical and empirical foundation supporting the use of radon balneotherapy for conditions like rheumatoid arthritis and ankylosing spondylitis.
Interpretation:

Limitations:
  • The review is not a systematic review and does not provide clinical practice recommendations.
  • Heterogeneity in radon therapy protocols limits quantitative synthesis of findings.
Conclusion:

Original Source(s)

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation

  • by Gabriel D. Rodrigues, Earric Lee, Benoit Dugué, Christian Hanshans, Maria Chiara Maccarone, Konstantinos Triantafyllias, Arnulf Hartl, Eugenijus Kaniusas, Sabrina Mörkl, Thomas E. Schmid, Goda-Camille Mickeviciute, Hannes Untner, Werner Klingler, Martin Offenbächer

  • June 24, 2026

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