To compare the sedative effects of remimazolam-based vs. midazolam-based sedation regimens in adults requiring ECMO, focusing on the incidence of delirium.
Key Findings:
Delirium occurred in 0% of patients in the remimazolam group vs. 27.3% in the midazolam group (p = 0.021).
Remimazolam group had shorter recovery time after decannulation (24.90 h vs. 29.84 h, p < 0.001).
Better-preserved muscle strength in remimazolam group (median MRC grade 1 vs. 0, p < 0.001).
Lower incidences of hypotension and bradycardia in the remimazolam group (both p < 0.05).
Interpretation:
Remove this section as it contains unsupported conclusions.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce bias.
Small sample size in each group.
Conclusion:
Revise to state only the findings without suggesting advantages or future research needs.
