Small-cell neuroendocrine carcinoma of the descending colon in a young adult: a case report - Summary - MDSpire

Small-cell neuroendocrine carcinoma of the descending colon in a young adult: a case report

  • By

  • Rong-Chao Zhou

  • Gang Zhou

  • Zhe Liang

  • May 25, 2026

  • 0 min

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Objective:

To report the diagnostic and therapeutic course of a young adult with small-cell neuroendocrine carcinoma (SCNEC) of the descending colon, focusing on atypical imaging features and their implications for diagnosis.

Key Findings:
  • SCNEC of the colon is rare, particularly in young adults.
  • Initial imaging findings can be confused with inflammatory diseases.
  • Atypical imaging features, such as circumferential colonic wall thickening, were observed.
  • The patient's young age is significant given the rarity of SCNEC.
Interpretation:

Colonic neuroendocrine neoplasms should be considered in the differential diagnosis for young patients with gastrointestinal symptoms, and early endoscopic biopsy is crucial for diagnosis to facilitate timely intervention.

Limitations:
  • The patient declined initial diagnostic procedures, delaying diagnosis and treatment, which may have affected the prognosis.
  • The rarity of SCNEC limits the generalizability of findings.
Conclusion:

This case emphasizes the need for awareness of atypical presentations of SCNEC in young patients.

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