Selecting the optimal method for assessment of hypertension-mediated organ damage: a personalized approach - Summary - MDSpire

Selecting the optimal method for assessment of hypertension-mediated organ damage: a personalized approach

  • By

  • Eva Gerdts

  • Athanase Benetos

  • Rosa Maria Bruno

  • Gregory Y H Lip

  • Helga Midtbø

  • Maria Lorenza Muiesan

  • Victor Aboyans

  • Gianfranco Parati

  • January 28, 2026

  • 0 min

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Objective:

To provide an expert opinion on optimizing the diagnosis of hypertension-mediated organ damage (HMOD) based on a synthesis of current hypertension guidelines.

Key Findings:
  • Basic HMOD screening should include ECG, serum creatinine, eGFR, and albumin-creatinine ratio for all hypertensive patients.
  • Advanced HMOD assessments are recommended based on initial evaluation findings and local resources, and may include echocardiography and imaging techniques.
  • HMOD is a marker of high cardiovascular risk and should be integrated into CVD risk assessment.
Interpretation:

HMOD reflects preclinical cardiovascular disease and significantly increases the risk of future cardiovascular events, necessitating careful assessment and management based on HMOD findings.

Limitations:
  • Variability in the availability of advanced diagnostic tools may affect the implementation of recommendations.
  • Clinical practice may differ from guideline recommendations due to individual patient factors and differing interpretations of guidelines.
Conclusion:

Basic assessment of HMOD is essential for all patients with hypertension, while advanced testing should be selectively applied based on initial findings.

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