Age at first cardiovascular diagnosis and risk of subsequent cardiovascular events in patients with different types of cardiovascular disease - Summary - MDSpire
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Age at first cardiovascular diagnosis and risk of subsequent cardiovascular events in patients with different types of cardiovascular disease
To examine the relationship between age at first cardiovascular disease (CVD) diagnosis and subsequent cardiovascular events across various CVD subtypes, including the impact of age on prognosis.
Key Findings:
Younger age at first CVD diagnosis is associated with a lower risk of subsequent cardiovascular events in patients with CeVD (HR per 10-year increase: 2.78; 95% CI 2.11–3.68) and women with PAD/AAA (HR 1.57; 95% CI 1.30–1.90).
Higher age at CVD diagnosis correlates with increased risk of subsequent events in CeVD for both men and women, and in women with PAD/AAA.
No significant associations were found for CAD patients or men with PAD/AAA.
Interpretation:
The findings suggest that younger patients with CeVD and women with PAD/AAA may benefit from more intensive secondary prevention strategies, highlighting the need for tailored approaches in these groups.
Limitations:
The study is limited to a single-center cohort, which may affect the generalizability of the results.
The analysis does not account for all potential confounding factors that could influence cardiovascular risk.
The single-center design may limit the diversity of the cohort.
Conclusion:
Younger age at first CVD diagnosis is linked to a lower risk of future cardiovascular events in specific CVD types, indicating the need for tailored prevention strategies.
by Martijn M Pieterse, Martin Teraa, Manon G van der Meer, Ynte M Ruigrok, Mike J L Peters, Ilonca Vaartjes, Frank L J Visseren, Jannick A N Dorresteijn, on behalf of the UCC-SMART Study Group
