Coexistence of Multiple Superficial Lipomatous Nevi and a Verrucous Nevus: A Case Study - Summary - MDSpire

Coexistence of Multiple Superficial Lipomatous Nevi and a Verrucous Nevus: A Case Study

  • By

  • Lixiu Chen

  • Wenjun Zeng

  • Guihong Zhu

  • Kun Zhang

  • April 24, 2026

  • 0 min

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Objective:

To report a rare case of coexistence of nevus lipomatosus cutaneous superficialis (NLCS) and verrucous epidermal nevus (VEN) in a single patient, highlighting its rarity.

Key Findings:
  • The patient was diagnosed with both NLCS and VEN based on clinical and histopathological findings.
  • The lesions were arranged in a band-like distribution and did not cross the midline.
  • This case suggests a possible common developmental origin for NLCS and VEN, indicating the need for further research.
Interpretation:

The coexistence of NLCS and VEN may indicate a shared embryonic developmental pathway, underscoring the importance of comprehensive evaluation of similar skin lesions.

Limitations:
  • The rarity of the case limits generalizability.
  • Further studies are needed to explore the embryological connections between these hamartomas.
Conclusion:

This case underscores the importance of considering combined hamartomas in patients with linear or zosteriform skin lesions and the necessity for multiple-site biopsies to avoid underdiagnosis.

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