Objective:

To analyze the burden of kidney cancer across socioeconomic development index (SDI) regions and understand the influence of specific socioeconomic factors such as income and education on disease trends.

Key Findings:

• Kidney cancer is the sixth and ninth most common malignant tumor in men and women, respectively, with a notable increase in incidence in Asia.
• In 2019, there were approximately 390,000 cases of kidney cancer globally, with a higher incidence in males, reflecting a significant gender disparity.
• Mortality rates for kidney cancer have stabilized or declined in many regions since the 1990s, attributed to better healthcare access and early diagnosis, although disparities remain.
• Asia has seen a 317.2% increase in kidney cancer incidence from 1990 to 2019, indicating significant challenges in prevention and treatment.
• Socioeconomic factors, particularly education levels, significantly influence kidney cancer outcomes, with lower education correlating with higher cancer death rates.

Interpretation:

The findings highlight the global disparities in kidney cancer incidence and mortality, emphasizing the need for targeted healthcare policies that consider socioeconomic factors.

Limitations:

• The study may not fully capture all regional variations in kidney cancer trends due to data limitations, including potential underreporting in low-income regions.
• Forecasting models may have inherent uncertainties that could affect the accuracy of future projections, particularly in rapidly changing healthcare environments.

Conclusion:

The study provides a comprehensive overview of kidney cancer trends and emphasizes the importance of addressing socioeconomic disparities in healthcare to improve outcomes, advocating for targeted interventions.