Case Report: Making room for radicality: balancing liver reserve and oncologic clearance in hilar cholangiocarcinoma through portal vein embolisation - Summary - MDSpire

Case Report: Making room for radicality: balancing liver reserve and oncologic clearance in hilar cholangiocarcinoma through portal vein embolisation

  • By

  • Elvin Jia Hong Lee

  • Zhun Shen Tan

  • Azlanudin Azman

  • Isa Azzaki Zainal

  • Muhammad Zahid Abdul Muien

  • Ian Chik

  • July 8, 2026

  • 0 min

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Objective:

To discuss the role of Portal Vein Embolization (PVE) in optimizing surgical outcomes for patients with hilar cholangiocarcinoma by enhancing future liver remnant (FLR) hypertrophy.

Approach:
  • Case Presentation: A 61-year-old male with Bismuth-Corlette type IIIA hilar cholangiocarcinoma underwent PVE to increase FLR from 34% to 60.5%, enabling safe extended right hepatectomy.
  • Surgical Techniques: The report highlights the use of PVE and discusses other liver hypertrophy techniques such as Liver Venous Deprivation (LVD) and ALPPS.
Key Findings:
  • PVE successfully induced FLR hypertrophy from 34% to 60.5%, allowing for safe extended hepatectomy without post-hepatectomy liver failure (PHLF).
  • The case emphasizes the importance of preoperative PVE in patients with marginal FLR.
Interpretation:

The case illustrates the successful conversion of a marginal FLR into an adequate physiological reserve through PVE, facilitating safe surgical resection in this patient with hilar cholangiocarcinoma.

Limitations:
  • The report is based on a single case study, which may limit the applicability of the findings to a broader patient population.
  • The infrequent performance of PVE suggests a need for more extensive experience and data to support its widespread use.
Conclusion:

This case highlights the critical role of preoperative PVE in enhancing surgical safety and outcomes for patients with hilar cholangiocarcinoma.

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