To investigate the correlation between R2* with fat fraction (FF) and bone mineral density (BMD), and to explore its role in the quantitative assessment of osteoporosis (OP).
Key Findings:
A total of 83 patients were enrolled, with good agreement in FF and R2* measurements (ICC = 0.917, 0.886).
Significant negative correlation found between FF and BMD of the vertebral body.
R2* values correlated with BMAT content and BMD, supporting its potential role in OP assessment.
Interpretation:
The study suggests that R2* and FF could serve as complementary metrics to BMD in assessing osteoporosis, particularly in the context of bone marrow composition.
Limitations:
The study's sample size was relatively small (83 patients).
Results may not be generalizable beyond the specific patient population studied.
Conclusion:
R2* and FF are promising biomarkers for the quantitative assessment of osteoporosis, warranting further research to validate their clinical utility.
