To report a case of acquired reactive perforating collagenosis (ARPC) in a patient with multiple systemic comorbidities.
Approach:
Case Presentation: A 55-year-old male with decompensated heart failure, type-2 diabetes, chronic renal failure, and hyperparathyroidism presented with pruritic skin lesions.
Diagnosis: Histopathology confirmed ARPC through the identification of cup-shaped epidermal invaginations and transepidermal extrusion of modified collagen.
Treatment: The patient was treated with Dermovate, omalizumab, fexofenadine, and body moisturizers, alongside management for glucose control and renal function.
Key Findings:
The patient was diagnosed with ARPC for the first time in Palestine.
He exhibited multiple pruritic papules with central keratotic plugs.
Histopathological findings confirmed the diagnosis of ARPC.
Interpretation:
The case illustrates the coexistence of ARPC with systemic comorbidities.
Limitations:
Only one case is reported, limiting generalizability.
Follow-up showed minimal improvement in pruritus and no change in skin lesions.
Conclusion:
ARPC is a rare dermatologic condition that may occur alongside various systemic diseases, necessitating increased clinical awareness.
