Health Benefits, Costs, and Cost-Effectiveness of Jail-Based Hepatitis C Elimination Strategies - Summary - MDSpire

Health Benefits, Costs, and Cost-Effectiveness of Jail-Based Hepatitis C Elimination Strategies

  • By

  • Lin Zhu

  • Lora N. Magaldi

  • Indrani A. Wagh

  • Eliza R. Ennis

  • Marissa B. Reitsma

  • Danica E. Kuncio

  • Eman Addish

  • Sandy R. Varghese

  • Nathan W. Furukawa

  • Amanda A. Honeycutt

  • Yijie Chen

  • Benjamin P. Linas

  • Joshua A. Salomon

  • May 1, 2026

  • 0 min

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Objective:

To evaluate the health benefits, costs, and cost-effectiveness of jail-based hepatitis C virus (HCV) elimination strategies specifically targeting people who inject drugs.

Key Findings:
  • Jail-based HCV interventions can significantly reduce viremia prevalence, indicating a direct impact on public health.
  • Direct-acting antiviral treatments enhance the feasibility of jail-based HCV care, suggesting a shift in treatment paradigms.
  • High loss to follow-up was observed due to early release before treatment completion, highlighting a critical barrier to effective care.
Interpretation:

Jail settings present unique opportunities and challenges for HCV elimination efforts, with potential public health benefits such as reduced transmission rates, despite financial disincentives for jails.

Limitations:
  • Short detention periods may hinder sufficient time for HCV testing and treatment, necessitating streamlined processes.
  • Staff shortages and turnover in jails complicate healthcare delivery, indicating a need for stable staffing solutions.
Conclusion:

Innovative jail-based HCV elimination strategies are essential for reaching and engaging people who inject drugs, potentially leading to broader community health benefits and addressing systemic barriers.

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