CT and MRI radiomics in cardiovascular risk prediction: a systematic review and meta-analysis by the EuSoMII Radiomics Auditing Group - Summary - MDSpire

CT and MRI radiomics in cardiovascular risk prediction: a systematic review and meta-analysis by the EuSoMII Radiomics Auditing Group

  • By

  • Armando Ugo Cavallo

  • Andrea Ponsiglione

  • Bernardo Pereira

  • Carlo Di Donna

  • Emmanouil Koltsakis

  • Federica Vernuccio

  • Mario Laudazi

  • Roberto Cannella

  • Salvatore Claudio Fanni

  • Tugba Akinci D’Antonoli

  • Renato Cuocolo

  • December 24, 2025

  • 0 min

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Objective:

To conduct a systematic review of studies applying radiomics to CT and MRI for cardiac disease evaluation and perform a meta-analysis of their diagnostic accuracy, focusing on cardiovascular events prediction from studies published up to March 2025.

Key Findings:
  • The median METRICS score for the evaluated studies was low, indicating poor methodological quality.
  • The meta-analysis provided pooled AUC values for the diagnostic accuracy of radiomics in predicting cardiovascular events, specifically [insert specific AUC values].
Interpretation:

The findings highlight the potential of radiomics in cardiovascular risk prediction but emphasize the need for improved methodological standards in research.

Limitations:
  • Heterogeneity in study methodologies may affect the reliability of results, particularly in terms of varying definitions and measurement techniques.
  • Limited number of studies meeting inclusion criteria for meta-analysis.
Conclusion:

Enhancing methodological quality through tools like METRICS is essential for advancing the clinical application of radiomics in cardiovascular imaging, thereby improving diagnostic accuracy and patient outcomes.

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