To systematically evaluate and select specific case definitions for the National Neurological Conditions Surveillance System (NNCSS) for Parkinson Disease (PD) surveillance and assess various data source types available to the CDC.
Key Findings:
Identified and screened 7954 citations, with 156 studies meeting eligibility criteria.
Included 23 validation studies and 133 nonvalidation studies, with 90% utilizing administrative data.
Nearly half of the studies (42%) were US-based, with Medicare being the most used data source.
Interpretation:
The systematic review highlights the complexity of PD diagnosis and emphasizes the need for robust surveillance systems to accurately track PD prevalence and inform targeted public health actions.
Limitations:
Potential bias in patient selection affecting study applicability; consider strategies to mitigate this bias.
Limited availability of national public health surveillance data for PD; recommend exploring partnerships for data collection.
Conclusion:
The findings support the need for standardized case definitions and reliable data sources for effective PD surveillance in the US, which could enhance public health responses.
