Performance of a quality control center supporting national antimicrobial resistance surveillance - Summary - MDSpire

Performance of a quality control center supporting national antimicrobial resistance surveillance

  • By

  • Dong Woo Shin

  • Hyunji Kim

  • Jeong Su Park

  • Kyoung Un Park

  • Min Hyuk Choi

  • Dokyun Kim

  • Seok Hoon Jeong

  • Hee Jung Kim

  • Young Ah Kim

  • Kwangjin Ahn

  • Young Uh

  • Yong Jun Kwon

  • Jong Hee Shin

  • Soo Hyun Kim

  • Jeong Hwan Shin

  • Hee Young Kang

  • Dong Chan Moon

  • Sung Young Lee

  • Songmee Bae

  • June 3, 2026

  • 0 min

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Objective:

To evaluate the quality assurance performance of the Korea Global Antimicrobial Resistance Surveillance System (Kor-GLASS) during its transition from Phase II to Phase III, emphasizing the significance of this transition.

Key Findings:
  • Overall categorical agreement (CA) in IPT exceeded 97% throughout the study period.
  • No EQA failures were observed among participating centers.
  • Major errors in Phase II decreased significantly in Phase III due to targeted corrective actions and educational interventions.
  • High concordance was observed in susceptibility testing for ceftazidime-avibactam, with discrepancies limited to near-breakpoint measurements.
  • Interlaboratory validation confirmed acceptable performance for AST of Haemophilus spp.
Interpretation:

A centralized, QCC-led quality assurance framework maintained stable and reliable AMR surveillance performance during system expansion, as evidenced by the findings.

Limitations:
  • The study only covers data from 2020 to 2024 and may not reflect long-term trends.
  • Findings are specific to the Kor-GLASS network and may not be generalizable to other AMR surveillance systems, with potential biases acknowledged.
Conclusion:

The QCC's quality assurance activities are reported to be essential for sustaining the credibility and future development of AMR surveillance systems, based on the findings.

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