A Secure User Interface for Preclinical Evaluation of AI in Patient Portal Message Management: Tutorial - Summary - MDSpire

A User-Friendly Interface for the Preclinical Assessment of AI in Managing Patient Portal Communications: A Guide

  • By

  • Kelly Gleason

  • Thomas Kidu

  • Vignesh Babu

  • Brian Hasselfeld

  • Jennifer Wolff

  • July 20, 2026

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Objective:

To present a technical feasibility report on a user interface-based sandbox developed for testing AI tools in patient portal message management within a secure research environment.

Approach:
  • Setting and Governance: Development and experiments were conducted in a secure research environment with institutional review board (IRB) approval, ensuring no production EHR systems were affected.
  • Software Stack and Architecture: The system was implemented using Python and Streamlit, featuring a modular backend for data handling, privacy, and AI task execution, with core packages for natural language processing and entity recognition.
Key Findings:
  • The sandbox allows for safe testing and iteration of AI outputs without impacting live EHR systems.
  • It supports secure experiments with real messages while ensuring patient safety and system stability.
  • The architecture is designed to facilitate updates and reproducibility.
Interpretation:

The developed sandbox provides a controlled environment for evaluating AI tools in patient portal communications, addressing the risks associated with direct integration into live EHR systems.

Limitations:
  • The sandbox is separate from live EHR systems, which may limit the applicability of findings to real-world settings.
  • The reliance on simulated data may not fully capture the complexities of actual patient interactions.
Conclusion:

The user-friendly interface and sandbox environment are essential for the rigorous testing of AI applications in patient portal communications, ensuring safety and effectiveness before deployment.

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