SARS-CoV-2 reinfection: a possible contributing factor to long COVID in children and adolescents - Summary - MDSpire

SARS-CoV-2 reinfection: a possible contributing factor to long COVID in children and adolescents

  • By

  • Rosela Lucero Chipol-Ceja

  • Jaime Morales-Romero

  • Carlos Alonso Rivero-López

  • María del Sagario Pérez-Callejas

  • Geovani López-Ortiz

  • Luis Del Carpio-Orantes

  • Claudia Iveth Spinoso-Torres

  • Santiago González-Periañez

  • María de Jesús Rodríguez-Cordoba

  • Liliana Ovando-Diego

  • Jorge Iván Zurutuza-Lorméndez

  • June 16, 2026

  • 0 min

Share

Objective:

To identify the prevalence, clinical characteristics, and potential associated factors of long COVID in children treated during the pandemic in a primary care unit, emphasizing the importance of understanding this condition in pediatric care.

Key Findings:
  • The prevalence of long COVID in the study population was 11.8% (95%CI 7.8%–17.5%).
  • Most frequent symptoms for 'persistence' included cough (50%) and rhinorrhea (15.4%).
  • Common symptoms for 'post-COVID conditions' included myalgia (33.3%), asthenia (26.7%), irritability (26.7%), and constipation (20%).
  • For children over 8 years, reinfection history (OR 9.7, 95%CI) and BMI (OR 1.1, 95%CI) were associated with long COVID; for those under 8 years, male sex (OR 4.7, 95%CI) was a significant factor.
Interpretation:

The study highlights the potential impact of reinfection and BMI on long COVID prevalence in older children, while male sex appears to be a risk factor in younger children, suggesting implications for healthcare practices.

Limitations:
  • Results are based on an exploratory analysis and should be interpreted with caution, considering potential biases in data collection.
  • The study's findings may not be generalizable beyond the specific population in Mexico.
Conclusion:

Approximately 12% of children and adolescents may be affected by long COVID, necessitating further research to understand and manage this condition, particularly through follow-up studies addressing identified gaps.

Original Source(s)

Related Content