Effects of home-based exercise on anxiety, depression, cancer-related fatigue, and quality of life in colorectal cancer patients: a meta-analysis of randomized controlled trials - Summary - MDSpire
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Effects of home-based exercise on anxiety, depression, cancer-related fatigue, and quality of life in colorectal cancer patients: a meta-analysis of randomized controlled trials
To determine the effects of home-based exercise on anxiety, depression, cancer-related fatigue, and quality of life in colorectal cancer (CRC) patients, highlighting its significance in improving patient care.
Home-based exercise improved quality of life (SMD = 0.64, 95% CI: 0.18 to 1.10, low certainty evidence).
No significant effect on depression levels (SMD = -0.76, 95% CI: -1.81 to 0.30, very low certainty evidence).
Interpretation:
Home-based exercise may serve as a complementary therapy for reducing anxiety and cancer-related fatigue while improving quality of life in CRC patients, but it does not significantly reduce depression levels, which has important implications for clinical practice.
Limitations:
Substantial heterogeneity in results among the studies reviewed.
Low certainty of evidence for outcomes due to limitations in the included studies.
Need for improved study design and validated outcome measures in future research.
Conclusion:
Home-based exercise is beneficial for managing anxiety and fatigue in CRC patients but does not effectively address depression. Future studies should enhance methodological rigor to overcome the limitations identified.
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