The Utility of Baseline Prognostic Nutritional Index (PNI) and Functional Status Among Hip Fracture and Distal Femur Fracture Patients - Summary - MDSpire

The Utility of Baseline Prognostic Nutritional Index (PNI) and Functional Status Among Hip Fracture and Distal Femur Fracture Patients

  • By

  • Jake R. McDermott

  • Jacquelyn J. Xu

  • Shivasuryan Vummidi

  • Jared M. Newman

  • Nishant Suneja

  • Michael J. Weaver

  • Eric H. Tischler

  • February 24, 2026

  • 0 min

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Objective:

To evaluate the predictive value of functional status compared to the Prognostic Nutritional Index (PNI) for postoperative mortality in patients with hip and distal femur fractures.

Key Findings:
  • 29.4% of the cohort were male, with a median age of 81.0 years, highlighting the demographic profile of the study population.
  • 76.8% of patients had independent functional status, indicating a generally healthier cohort.
  • Functional status was identified as a significant predictor of postoperative outcomes, including mortality, suggesting its critical role in preoperative assessments.
Interpretation:

Functional status appears to be a more critical predictor of postoperative mortality than PNI in geriatric patients with hip and distal femur fractures, which may influence preoperative evaluation strategies.

Limitations:
  • The study is retrospective and may be subject to selection bias, potentially affecting the generalizability of the findings.
  • Functional status assessment is subjective and may vary between evaluators, which could introduce variability in the results.
Conclusion:

Functional capacity should be prioritized over PNI in assessing preoperative health and predicting outcomes in patients with fragility fractures, aligning with emerging evidence in the field.

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