Development and internal validation of a nomogram to predict perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia: a retrospective cohort study - Summary - MDSpire

Development and internal validation of a nomogram to predict perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia: a retrospective cohort study

  • By

  • Yingbo Ren

  • Lei Huang

  • Ling Chen

  • Feng Liu

  • Lihong Song

  • Qingyuan Li

  • Xin Wang

  • Hongyan Li

  • June 10, 2026

  • 0 min

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Objective:

To develop and internally validate a nomogram for predicting perioperative hypothermia in patients undergoing laparoscopic gynecologic surgery under general anesthesia, thereby enhancing individualized patient care.

Key Findings:
  • 279 out of 424 patients (65.8%) developed perioperative hypothermia.
  • The final model demonstrated good discrimination with an AUC of 0.788 (95% CI: X-Y) in the training cohort and 0.810 (95% CI: A-B) in the validation cohort.
  • At the training-derived Youden cutoff, sensitivity was 0.623 and specificity was 0.853 in the training cohort; sensitivity was 0.925 and specificity was 0.580 in the validation cohort.
Interpretation:

The nomogram effectively estimates the risk of perioperative hypothermia based on age, body mass index, and operative time in laparoscopic gynecologic surgery, potentially improving clinical outcomes.

Limitations:
  • The study is limited to a single center, which may affect the generalizability of the findings to broader populations.
  • External validation in independent cohorts is required before broader clinical implementation to confirm the model's applicability.
Conclusion:

A nomogram was developed to assist in estimating the risk of perioperative hypothermia in adult patients undergoing laparoscopic gynecologic surgery, potentially aiding in individualized temperature management.

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