To summarize the immunomodulatory mechanisms and evidence of Astragalus membranaceus and its derivatives in the treatment of specific digestive diseases.
Approach:
Key Findings:
Astragalus membranaceus and its derivatives exhibit multi-target regulatory effects.
They modulate core signaling pathways and influence immune cell function and gut microbiota composition.
The agents rebalance immune axes such as Th1/Th2 and Treg/Th17.
Interpretation:
The review provides insights into the mechanisms of Astragalus membranaceus and its active compounds.
Limitations:
Current studies may have methodological flaws.
The review is limited to full-text articles in English or Chinese.
Conclusion:
The findings suggest a role for Astragalus membranaceus in managing gastrointestinal disorders through immune tolerance regulation.
