To report a case of cervical lymphadenitis in a pediatric patient caused by Pseudomonas aeruginosa and highlight the utility of metagenomic next-generation sequencing in diagnosis.
Key Findings:
Cervical lymphadenitis can be caused by Gram-negative bacteria, specifically Pseudomonas aeruginosa.
Metagenomic next-generation sequencing effectively identified the pathogen when traditional cultures failed.
The patient showed significant clinical improvement following targeted antibiotic therapy.
Interpretation:
The case underscores the importance of considering opportunistic pathogens in pediatric infections and the role of advanced sequencing technologies in diagnosis.
Limitations:
The study is based on a single case, limiting generalizability.
The low coverage rate of P. aeruginosa in mNGS results may affect the reliability of the diagnosis.
Conclusion:
Metagenomic next-generation sequencing is a valuable tool in diagnosing atypical infections in pediatric patients, particularly when conventional methods are inconclusive.
