Trends and Key Areas of Research in the Pathophysiology, Imaging, and Treatment of Type 3 Macular Neovascularization (MNV3) Associated with Age-Related Macular Degeneration (AMD) - Summary - MDSpire

Trends and Key Areas of Research in the Pathophysiology, Imaging, and Treatment of Type 3 Macular Neovascularization (MNV3) Associated with Age-Related Macular Degeneration (AMD)

  • By

  • Ye Li

  • Xiangyu Fu

  • Ling Huang

  • Lirong Xiao

  • Danian Chen

  • April 24, 2026

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Objective:

To provide an overview of the research hotspots and directions of type 3 macular neovascularization (MNV3) in age-related macular degeneration specifically through bibliometric analysis.

Approach:
    Key Findings:
    • The United States leads in MNV3 research output from 2001 to 2026.
    • Kim JW is the most prolific author; Yannuzzi LA is the most cited.
    • High-frequency keywords include 'ranibizumab', 'photodynamic therapy', and 'optical coherence tomography'.
    • Emerging research hotspots involve 'artificial intelligence', 'biomarker', and 'microglia'.
    • Research topics are categorized into pathogenesis, imaging, therapy, and clinical prognosis.
    Interpretation:

    The analysis highlights significant advancements and collaborative efforts in MNV3 research, indicating a growing interest and evolving understanding of the condition, which may guide future research directions.

    Limitations:
    • The study is limited to publications in English, which may introduce language bias.
    • Only two databases were used for literature retrieval.
    Conclusion:

    This bibliometric analysis elucidates research hotspots and directions in MNV3, providing a foundation for future investigations in this evolving field.

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