24-h NIHSS score is the strongest prognostic predictor of 90-day outcome in cardioembolic stroke patients with anterior circulation occlusion after endovascular thrombectomy - Summary - MDSpire
Advertisement
24-h NIHSS score is the strongest prognostic predictor of 90-day outcome in cardioembolic stroke patients with anterior circulation occlusion after endovascular thrombectomy
To evaluate and compare the predictive performance of NIHSS assessed at baseline, at 24 h, and derived change metrics (ΔNIHSS and percent ΔNIHSS) for 90-day unfavorable functional outcomes in cardioembolic stroke patients post-endovascular thrombectomy.
Key Findings:
24-h NIHSS was confirmed as an independent predictor of 90-day outcomes.
ROC analysis showed 24-h NIHSS had the highest predictive power (AUC = 0.850).
The optimal cut-off value for 24-h NIHSS was ≥12, with 82.2% sensitivity and 75.6% specificity.
Combining 24-h NIHSS with other metrics did not improve predictive performance.
Interpretation:
The 24-h NIHSS score is the most effective prognostic indicator for unfavorable functional outcomes in cardioembolic stroke patients after EVT, surpassing baseline NIHSS and change metrics.
Limitations:
Retrospective design may introduce selection bias.
Single-center study limits generalizability of findings.
Potential confounding factors may not have been accounted for.
Conclusion:
The 24-h NIHSS score serves as an early and effective tool for prognostic stratification in cardioembolic stroke patients post-EVT.
