A triad of hypertension, heart failure, and glomerular injury in subacute Kawasaki disease: a case report and literature review - Summary - MDSpire

A triad of hypertension, heart failure, and glomerular injury in subacute Kawasaki disease: a case report and literature review

  • By

  • Qian Liu

  • Jing Liu

  • Ting Kang

  • Yuan Long

  • May 13, 2026

  • 0 min

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Objective:

To present a case of a child with Kawasaki disease who developed hypertension, heart failure, and kidney damage during the subacute phase despite initial successful treatment, highlighting the need for ongoing monitoring.

Key Findings:
  • The patient exhibited a triad of hypertension, acute heart failure, and early glomerular injury during the subacute phase, indicating potential long-term risks.
  • Despite normalization of inflammatory markers, vascular dysfunction persisted, suggesting a need for ongoing monitoring.
  • The case highlights the importance of assessing blood pressure and cardiac function in the subacute phase of Kawasaki disease to prevent complications.
Interpretation:

The findings suggest that Kawasaki disease can lead to significant vascular complications even after successful initial treatment, necessitating a reevaluation of monitoring protocols during the subacute phase to ensure patient safety.

Limitations:
  • The case study is based on a single patient, limiting generalizability and necessitating caution in applying findings broadly.
  • Long-term outcomes and the full spectrum of vascular complications in Kawasaki disease require further investigation to inform clinical practice.
Conclusion:

This case underscores the need for vigilant monitoring of cardiovascular and renal health in Kawasaki disease patients during the subacute phase, even when systemic inflammation appears resolved, to mitigate potential complications.

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