Link Between Glucose-to-Potassium Ratio and Outcomes in Critically Ill Patients with Sepsis and Cancer: A Retrospective Analysis Utilizing the MIMIC Database - Summary - MDSpire

Link Between Glucose-to-Potassium Ratio and Outcomes in Critically Ill Patients with Sepsis and Cancer: A Retrospective Analysis Utilizing the MIMIC Database

  • By

  • Bin Feng

  • Wenxin Shen

  • Sheng Cheng

  • Ping Wang

  • Yi Zhang

  • January 8, 2026

  • 0 min

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Objective:

To elucidate how baseline GPR at ICU entry influences all-cause mortality (ACM) among critically ill individuals with sepsis and malignancy, highlighting its potential as a prognostic tool.

Key Findings:
  • Higher GPR was associated with increased all-cause mortality in critically ill patients with sepsis and cancer, suggesting a need for targeted interventions.
  • Patients were categorized into four cohorts based on GPR quartiles, with significant differences in mortality outcomes, indicating the potential for risk stratification.
Interpretation:

The study suggests that GPR may serve as a prognostic biomarker for assessing mortality risk in critically ill patients with sepsis and malignancy, warranting further exploration in clinical settings.

Limitations:
  • Retrospective design may introduce selection bias.
  • Data derived from a single center may limit generalizability.
  • Potential confounding factors not accounted for in the analysis.
Conclusion:

Baseline GPR at ICU entry is a potential prognostic indicator for mortality in critically ill patients with sepsis and cancer, warranting further investigation for clinical application across diverse populations.

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