To analyze the impact of vital signs, tcpCO2 dynamics, and patient characteristics on the difference of tcpCO2 and capillary pCO2 (ΔpCO2) in extremely preterm infants during their first week of life.
Approach:
Method: label
Method: text
Key Findings:
Postnatal age, mean fraction of inspired oxygen, tcpCO2, capillary pCO2, last tcpCO2, and last ΔpCO2 were positively associated with ΔpCO2.
Gestational age and hemoglobin were negatively associated with ΔpCO2.
Interpretation:
The identified candidate parameters may enhance the non-invasive estimation of pCO2 from tcpCO2 in extremely preterm infants.
Limitations:
The study was conducted in a single NICU, which may limit generalizability.
Exclusion criteria may have led to selection bias.
Conclusion:
The findings suggest that specific patient characteristics and vital signs can influence the accuracy of tcpCO2 measurements in extremely preterm infants.
